Prostate / Prostate Cancer News From Medical News Today
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Researchers Develop Tool To Help Study Prostate Cancer
Mar 13, 2010 12:00am
Van Andel Research Institute (VARI) researchers have developed a new method to better study the cells that line and protect the prostate in relation to the development of cancer. Using the model, they found that normal cells and cancer cells depend on different factors to survive, which could aid in...
Abbott Seeks FDA Approval Of A New Six-Month 45-mg Formulation Of Lupron(R) Depot For The Palliative Treatment Of Advanced Prostate Cancer
Mar 12, 2010 2:00am
The U.S. Food and Drug Administration (FDA) has accepted for review the supplemental new drug application (sNDA) of a new six-month 45-mg formulation of Lupron® Depot (leuprolide acetate for depot suspension) for use in the palliative treatment of advanced prostate cancer. Palliative treatment helps to relieve symptoms associated...
AdMeTech Hails New Research That Shows Promise Of MRI To Discriminate Aggressive Prostate Cancer From Dormant Disease
Mar 11, 2010 2:00am
New preliminary data from a pilot study in the Netherlands indicates that imaging tools may help address the most challenging clinical dilemma of prostate cancer care as identified by the hearing of the House Oversight and Government Reform Committee and its expert witnesses last week: to treat or not treat,...
First Inherited Prostate Cancer Genetic Mutation Found In African-American Men
Mar 10, 2010 11:00pm
Shahriar Koochekpour, MD, PhD, Assistant Professor of Microbiology and Immunology, Biochemistry and Molecular Biology, and Genetics at LSU Health Sciences Center New Orleans, led research that has discovered, for the first time, a genetic mutation in African-American men with a family history of prostate cancer who are at increased risk...
Reovirus May Be A Novel Approach To Prostate Cancer Treatment
Mar 10, 2010 2:00am
Researchers in Canada have detected a novel oncolytic viral therapy against prostate cancer with use of a virus called the reovirus, according to study results published in Cancer Research, a journal of the American Association for Cancer Research......
Millennium Announces First Clinical Data For TAK-700 Prostate Molecule At ASCO GU
Mar 9, 2010 4:00pm
Millennium: The Takeda Oncology Company today announced the presentation of safety, pharmacokinetic and efficacy data from the Phase I portion of a Phase I/II clinical trial evaluating TAK-700 in patients with metastatic castration resistant prostate cancer (mCRPC)......
Prostate Cancer Therapy Correlates To Specialist Seen
Mar 9, 2010 12:00am
New research published in today's issue of the Archives of Internal Medicine (Vol. 170, No. 5), by an investigator at The Cancer Institute of New Jersey (CINJ) and colleagues at Memorial Sloan-Kettering Cancer Center in New York, shows that the type of specialist that men with localized prostate cancer see...
PROGENSA(R) PCA3 Assay Can Help Guide Repeat Prostate Biopsy Decisions, Data Presented At Leading Medical Meeting Confirm
Mar 9, 2010 12:00am
Gen-Probe's (Nasdaq: GPRO) PROGENSA® PCA3 assay can help determine whether men suspected of having prostate cancer should undergo a repeat biopsy, according to data from the two largest studies to date of the molecular urine test. The studies were presented last week at the American Society of Clinical Oncology's...
FDA Approves First Generic Tamsulosin To Treat Enlarged Prostate Gland
Mar 3, 2010 4:00am
The U.S. Food and Drug Administration approved the first generic version of Flomax Capsules 0.4 mg (tamsulosin hydrochloride) to treat benign prostatic hyperplasia (BPH), a condition in which an enlarged prostate gland causes problems with urination......
Prostate Cancer Surgeons "Feel" With Their Eyes
Mar 2, 2010 12:00am
Robotic surgical technology with its three-dimensional, high-definition view gives surgeons the sensation of touch, even as they operate from a remote console. A new study describes the phenomenon, called intersensory integration, and reports that surgical outcomes for prostate cancer surgery using minimally invasive robotic technology compare favorably with traditional invasive...
Inclement East Coast Weather Delays ProUroScan(TM) FDA Review
Feb 27, 2010 1:00am
ProUroCare Medical, Inc. (OCT Bulletin Board: PUMD, PUMDU, PUMDW), a provider of proprietary medical imaging products, indicates that the Food and Drug Administration has informed the industry that the processing of 510(k) applications, which includes the ProUroScan™ prostate imaging system, has been delayed because of the inclement weather in February...
Effective Prostate Cancer Treatment Discovery
Feb 27, 2010 12:00am
Monash University biomedical scientists have identified a new way to treat castrate resistant cells in prostate cancer sufferers - the most common cancer in Australian men. For more than 60 years the main way to treat men with prostate cancer has involved removing the hormones that fuel growth of the...
Gleason Score And Laterality Concordance Between Prostate Biopsy And Prostatectomy Specimens
Feb 27, 2010 12:00am
UroToday.com - Treatment decisions in prostate cancer are guided by Gleason grade and laterality (unilateral vs. bilateral) findings on prostate needle biopsy which samples a small proportion of the prostate. Surgical decisions with respect to nerve sparing and lymph node dissection are also influenced by prostate biopsy findings......
Impact Of Positive Surgical Margins After Radical Prostatectomy Differs By Disease Risk Group
Feb 26, 2010 12:00am
UroToday.com - There is great controversy regarding the prognostic value of positive surgical margins (PSM) after radical prostatectomy. In studies that have demonstrated an impact of PSM on the prognosis of prostate cancer, several clinical and pathological features of the disease were found to be associated with such an impact......
Prostate Cancer Detection Rate And Predictive Factors In Patients Undergoing Ultrasonography-guided Transperineal Saturation Biopsies Of The Prostate
Feb 24, 2010 1:00am
UroToday.com - With regard to the prognostic factors predicting the diagnosis of prostate cancer, in our analysis, prostate volume was the unique clinical and pathological variable significantly associated with the incidence of prostate cancer in multivariate analysis [1]......
What It Might Take To Unravel The 'Lean Mean Machine' That Is Cancer
Feb 24, 2010 12:00am
Scientists from Sydney's Garvan Institute of Medical Research have published a paper, online in Nature Cell Biology, describing gene expression in a prostate cancer cell: more sweeping, more targeted and more complex than we could ever have imagined, even five years ago......
The Epstein Criteria Predict For Organ-Confined But Not Insignificant Disease And A High Likelihood Of Cure At Radical Prostatectomy
Feb 23, 2010 1:00am
UroToday.com - Active surveillance is gaining popularity as a management strategy for newly diagnosed low-grade prostate cancer. In 1994, Epstein reported PSA- and needle biopsy-based criteria for identifying potentially biologically insignificant tumors that might be safely managed by initial surveillance......
AUA 2010 Annual Scientific Meeting To Feature Latest In Urology, Cancer Research
Feb 22, 2010 4:00am
More than 15,000 urologists, researchers, healthcare professionals and exhibitors will gather in San Francisco, CA, for the American Urological Association's (AUA) 2010 Annual Scientific Meeting, which will be held at the Moscone Center, May 29-June 3, 2010......
Similar Outcomes In Both Open And Laparoscopic Prostate Surgery
Feb 22, 2010 3:00am
Of the 200,000 men newly diagnosed with prostate cancer each year in the United States, about one-third will undergo surgical treatment. Although open radical prostatectomy (ORP) is regarded as the standard treatment, laparoscopic radical prostatectomy (LRP) with or without robotic assistance is becoming more common......
The Connections Between Stem Cells And Cancer
Feb 22, 2010 2:00am
Researchers have a new tool to understand how cancers grow -- and with it a new opportunity to identify novel cancer drugs. They've been able to break apart human prostate tissue, extract the stem cells in that tissue, and alter those cells genetically so that they spur cancer......
Cholesterol Regulation Alterations Contribute To Intratumoral Androgen Production During Progression To CRPC In A Mouse Xenograft Model
Feb 22, 2010 12:00am
UroToday.com - It is known that in castration-resistant prostate cancer (CRPC) the androgen receptor (AR) is expressed and remains active and prostate cancer (CaP) cells are able to produce their own supply of androgens. These intracrine androgens are synthesized by the increased activity of steroidogenic enzymes that use cholesterol...
A Randomized Trial Of External Beam Radiotherapy Versus Cryoablation In Patients With Localized Prostate Cancer
Feb 21, 2010 9:00am
UroToday.com - This type of trial is very difficult to conduct, resulting in slow accrual, and ultimately, early closure. Thus the study is underpowered. Other shortcomings are pointed out in our discussion......
Carbonic Anhydrase IX Expression In Prostate Cancer
Feb 21, 2010 1:00am
UroToday.com - Tumor hypoxia plays a role in tumor progression and chemotherapy resistance through reduced apoptosis, increased proliferation and angiogenesis. Hypoxic cell metabolism switches to anaerobic glycolysis and the production of acidic metabolites that facilitate cell survival and tumorigenesis......
Predictors Of Positive Surgical Margins After Laparoscopic Robot Assisted Radical Prostatectomy
Feb 20, 2010 1:00am
UroToday.com - In the past it has been suggested that the use of robot assisted laparoscopic radical prostatectomy (RALP) could be associated with a significant and swift reduction in positive surgical margins (PSM) rates......
Has The Advent Of Minimally Invasive Surgery Altered The Risk Profile Of Patients Undergoing Prostatectomy?
Feb 20, 2010 1:00am
UroToday.com - A report from Columbia University Department of Urology in the online edition of Urology assessed whether the introduction of minimally invasive surgery (MIS) has altered the selection characteristics of patients undergoing radical prostatectomy (RP). They did not find this to be the case......
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